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Welcome to BIOISIS ... the resource for macromolecular SAXS.
Experimental Highlight
Splicing factor complex of phosphorylated (P)SF1 residues 1-255 and U2AF65 residues 148-375
Low_res_thumbnail Human SF1 ULM-KH-QUA2, which is phosphorylated on Ser80Ser82, bound to U2AF65 RRM1-RRM2-UHM in a splicing factor complex.
    

Recent Posts

SCATTER 3.0  

Scatter has been updated to release 3.0. The program was completely re-written and utilizes several new structures for handling datasets. PDB files can be dropped in like *.dat files which will then create corresponding P®-distribution function and Intensity files. This is useful for comparing models in real-space against experimental data. There is also a new archiving feature for taking selected data and writing them to a separate directory with associated image files. The release has been tested for the past 4 months and should be stable (requires Jave 1.7 or greater).


RECONSTRUCTION OF SAXS PROFILES FROM PROTEIN STRUCTURES  

Excellent review on SAXS, this should be required reading material for anyone wanting to learn SAXS.


DENFERT: BEAD MODELING WITH HYDRATION  

New dummy atom modeling algorithm that uses the Debye equation instead of spherical harmonic expansions. The algorithm attempts to model the hydration layer assuming a biphasic composition of the scattering volume.


SCATTER 2.2B RELEASED  

Scatter 2.2b has been released and features several updates. Loading files is much faster due to truncation of the data for autoRg calculations. Scatter can now calculate P®-distributions from PDB files for easy direct comparison in P® plots. The Subtraction Tab has been improved, and has been adapted for SEC SAXS data. Please see the tutorial for more information.